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Pharmacokinetics and Brain Distribution of the Active Components of DA-9805, Saikosaponin A, Paeonol and Imperatorin in Rats

DA-9805 is a botanical anti-Parkinson’s drug candidate formulated from ethanol extracts of the root of Bupleurum falcatum, the root cortex of Paeonia suffruticosa, and the root of Angelica dahurica. The pharmacokinetics (PKs) and brain distribution of active/representative ingredients of DA-9805, Sa...

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Detalles Bibliográficos
Autores principales: Kwon, Mi Hye, Jeong, Jin Seok, Ryu, Jayoung, Cho, Young Woong, Kang, Hee Eun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160927/
https://www.ncbi.nlm.nih.gov/pubmed/30127277
http://dx.doi.org/10.3390/pharmaceutics10030133