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Bioavailability Enhancement of Poorly Water-Soluble Drugs via Nanocomposites: Formulation–Processing Aspects and Challenges

Drug nanoparticles embedded in a dispersant matrix as a secondary phase, i.e., drug-laden nanocomposites, offer a versatile delivery platform for enhancing the dissolution rate and bioavailability of poorly water-soluble drugs. Drug nanoparticles are prepared by top-down, bottom-up, or combinative a...

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Detalles Bibliográficos
Autores principales: Bhakay, Anagha, Rahman, Mahbubur, Dave, Rajesh N., Bilgili, Ecevit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160929/
https://www.ncbi.nlm.nih.gov/pubmed/29986543
http://dx.doi.org/10.3390/pharmaceutics10030086