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Systematic Development of Self-Nanoemulsifying Liquisolid Tablets to Improve the Dissolution and Oral Bioavailability of an Oily Drug, Vitamin K1

The purpose of this study is to improve the dissolution and oral bioavailability of an oily drug, vitamin K1 (VK1) by combination of self-nanoemulsifying and liquisolid technologies. The optimal liquid self-nanoemulsifying drug delivery systems (SNEDDS) formulation including VK1 (oil), mixture of so...

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Detalles Bibliográficos
Autores principales: Tong, Yongtao, Wang, Yuli, Yang, Meiyan, Yang, Jiahui, Chen, Lu, Chu, Xiaoyang, Gao, Chunhong, Jin, Qian, Gong, Wei, Gao, Chunsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160939/
https://www.ncbi.nlm.nih.gov/pubmed/30021949
http://dx.doi.org/10.3390/pharmaceutics10030096