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Systematic Development of Self-Nanoemulsifying Liquisolid Tablets to Improve the Dissolution and Oral Bioavailability of an Oily Drug, Vitamin K1
The purpose of this study is to improve the dissolution and oral bioavailability of an oily drug, vitamin K1 (VK1) by combination of self-nanoemulsifying and liquisolid technologies. The optimal liquid self-nanoemulsifying drug delivery systems (SNEDDS) formulation including VK1 (oil), mixture of so...
Autores principales: | Tong, Yongtao, Wang, Yuli, Yang, Meiyan, Yang, Jiahui, Chen, Lu, Chu, Xiaoyang, Gao, Chunhong, Jin, Qian, Gong, Wei, Gao, Chunsheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160939/ https://www.ncbi.nlm.nih.gov/pubmed/30021949 http://dx.doi.org/10.3390/pharmaceutics10030096 |
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