Proximal Pathway Enrichment Analysis for Targeting Comorbid Diseases via Network Endopharmacology

The past decades have witnessed a paradigm shift from the traditional drug discovery shaped around the idea of “one target, one disease” to polypharmacology (multiple targets, one disease). Given the lack of clear-cut boundaries across disease (endo)phenotypes and genetic heterogeneity across patien...

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Detalles Bibliográficos
Autores principales: Aguirre-Plans, Joaquim, Piñero, Janet, Menche, Jörg, Sanz, Ferran, Furlong, Laura I., Schmidt, Harald H. H. W., Oliva, Baldo, Guney, Emre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160959/
https://www.ncbi.nlm.nih.gov/pubmed/29932108
http://dx.doi.org/10.3390/ph11030061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160959/
https://www.ncbi.nlm.nih.gov/pubmed/29932108
http://dx.doi.org/10.3390/ph11030061

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