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Proximal Pathway Enrichment Analysis for Targeting Comorbid Diseases via Network Endopharmacology
The past decades have witnessed a paradigm shift from the traditional drug discovery shaped around the idea of “one target, one disease” to polypharmacology (multiple targets, one disease). Given the lack of clear-cut boundaries across disease (endo)phenotypes and genetic heterogeneity across patien...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160959/ https://www.ncbi.nlm.nih.gov/pubmed/29932108 http://dx.doi.org/10.3390/ph11030061 |