Dissolution Enhancement in Cocoa Extract, Combining Hydrophilic Polymers through Hot-Melt Extrusion

The aim of this study was to improve the physicochemical properties of cocoa extract (CE) using hot-melt extrusion (HME) for pharmaceutical proposes. A mixture design was applied using three distinct hydrophilic polymeric matrices (Soluplus, Plasdone S630, and Eudragit E). Systems obtained by HME we...

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Detalles Bibliográficos
Autores principales: Pinho, Ludmila A. G., Souza, Saulo G., Marreto, Ricardo N., Sa-Barreto, Livia L., Gratieri, Tais, Gelfuso, Guilherme M., Cunha-Filho, Marcilio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160995/
https://www.ncbi.nlm.nih.gov/pubmed/30134594
http://dx.doi.org/10.3390/pharmaceutics10030135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160995/
https://www.ncbi.nlm.nih.gov/pubmed/30134594
http://dx.doi.org/10.3390/pharmaceutics10030135

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