In Vitro Stimulation of Multidrug Resistance-Associated Protein 2 Function Is Not Reproduced In Vivo in Rats

Previously we reported that coproporphyrin-I (CP-I) is an optimal probe substrate for multidrug resistance-associated protein 2 (MRP2), and stimulation of MRP2-mediated transport is probe substrate-dependent. In the present investigation, we assessed if the in vitro stimulation is physiologically re...

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Detalles Bibliográficos
Autores principales: Gilibili, Ravindranath Reddy, Kurawattimath, Vishwanath, Murali, Bokka Venkata, Lai, Yurong, Mariappan, T. Thanga, Shen, Hong, Chatterjee, Sagnik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161027/
https://www.ncbi.nlm.nih.gov/pubmed/30096834
http://dx.doi.org/10.3390/pharmaceutics10030125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161027/
https://www.ncbi.nlm.nih.gov/pubmed/30096834
http://dx.doi.org/10.3390/pharmaceutics10030125

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