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A Lamin-Binding Ligand Inhibits Homologous Recombination Repair of DNA Double-Strand Breaks

[Image: see text] Nuclear lamins are type V intermediate filament proteins. Lamins, including LA, LB1, LB2, and LC, are the major protein components forming the nuclear lamina to support the mechanical stability of the mammalian cell nucleus. Increasing evidence has shown that LA participates in hom...

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Detalles Bibliográficos
Autores principales: Li, Bingbing X., Chen, Jingjin, Chao, Bo, Zheng, Yixian, Xiao, Xiangshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161055/
https://www.ncbi.nlm.nih.gov/pubmed/30276254
http://dx.doi.org/10.1021/acscentsci.8b00379