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A Lamin-Binding Ligand Inhibits Homologous Recombination Repair of DNA Double-Strand Breaks
[Image: see text] Nuclear lamins are type V intermediate filament proteins. Lamins, including LA, LB1, LB2, and LC, are the major protein components forming the nuclear lamina to support the mechanical stability of the mammalian cell nucleus. Increasing evidence has shown that LA participates in hom...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161055/ https://www.ncbi.nlm.nih.gov/pubmed/30276254 http://dx.doi.org/10.1021/acscentsci.8b00379 |