Chemogenetic Approach Using Ni(II) Complex–Agonist Conjugates Allows Selective Activation of Class A G-Protein-Coupled Receptors

[Image: see text] Investigating individual G-protein-coupled receptors (GPCRs) involved in various signaling cascades can unlock a myriad of invaluable physiological findings. One of the promising strategies for addressing the activity of each subtype of receptor is to design chemical turn-on switch...

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Detalles Bibliográficos
Autores principales: Kubota, Ryou, Nomura, Wataru, Iwasaka, Takuma, Ojima, Kento, Kiyonaka, Shigeki, Hamachi, Itaru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161059/
https://www.ncbi.nlm.nih.gov/pubmed/30276255
http://dx.doi.org/10.1021/acscentsci.8b00390

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161059/
https://www.ncbi.nlm.nih.gov/pubmed/30276255
http://dx.doi.org/10.1021/acscentsci.8b00390

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