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Chemogenetic Approach Using Ni(II) Complex–Agonist Conjugates Allows Selective Activation of Class A G-Protein-Coupled Receptors
[Image: see text] Investigating individual G-protein-coupled receptors (GPCRs) involved in various signaling cascades can unlock a myriad of invaluable physiological findings. One of the promising strategies for addressing the activity of each subtype of receptor is to design chemical turn-on switch...
Autores principales: | Kubota, Ryou, Nomura, Wataru, Iwasaka, Takuma, Ojima, Kento, Kiyonaka, Shigeki, Hamachi, Itaru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161059/ https://www.ncbi.nlm.nih.gov/pubmed/30276255 http://dx.doi.org/10.1021/acscentsci.8b00390 |
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