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Oral Bioavailability and Lymphatic Transport of Pueraria Flavone-Loaded Self-Emulsifying Drug-Delivery Systems Containing Sodium Taurocholate in Rats

We developed self-microemulsifying drug-delivery systems (SMEDDS), including bile salts, to improve the oral bioavailability of pueraria flavones (PFs). The physical properties of the SMEDDS using Cremophor RH 40, and bile salts as mixed surfactants at weight ratios of 10:0–0:10 were determined. The...

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Detalles Bibliográficos
Autores principales: Qiao, Jin, Ji, Danyang, Sun, Shilin, Zhang, Guangyuan, Liu, Xin, Sun, Bingxue, Guan, Qingxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161070/
https://www.ncbi.nlm.nih.gov/pubmed/30189624
http://dx.doi.org/10.3390/pharmaceutics10030147