Design, Synthesis, In Vitro, and Initial In Vivo Evaluation of Heterobivalent Peptidic Ligands Targeting Both NPY(Y(1))- and GRP-Receptors—An Improvement for Breast Cancer Imaging?

Heterobivalent peptidic ligands (HBPLs), designed to address two different receptors independently, are highly promising tumor imaging agents. For example, breast cancer has been shown to concomitantly and complementarily overexpress the neuropeptide Y receptor subtype 1 (NPY(Y(1))R) as well as the...

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Detalles Bibliográficos
Autores principales: Vall-Sagarra, Alicia, Litau, Shanna, Decristoforo, Clemens, Wängler, Björn, Schirrmacher, Ralf, Fricker, Gert, Wängler, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161111/
https://www.ncbi.nlm.nih.gov/pubmed/29973529
http://dx.doi.org/10.3390/ph11030065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161111/
https://www.ncbi.nlm.nih.gov/pubmed/29973529
http://dx.doi.org/10.3390/ph11030065

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