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Co-Amorphous Solid Dispersions for Solubility and Absorption Improvement of Drugs: Composition, Preparation, Characterization and Formulations for Oral Delivery

The amorphous solid state offers an improved apparent solubility and dissolution rate. However, due to thermodynamic instability and recrystallization tendencies during processing, storage and dissolution, their potential application is limited. For this reason, the production of amorphous drugs wit...

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Detalles Bibliográficos
Autores principales: Karagianni, Anna, Kachrimanis, Kyriakos, Nikolakakis, Ioannis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161132/
https://www.ncbi.nlm.nih.gov/pubmed/30029516
http://dx.doi.org/10.3390/pharmaceutics10030098