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Co-Amorphous Solid Dispersions for Solubility and Absorption Improvement of Drugs: Composition, Preparation, Characterization and Formulations for Oral Delivery
The amorphous solid state offers an improved apparent solubility and dissolution rate. However, due to thermodynamic instability and recrystallization tendencies during processing, storage and dissolution, their potential application is limited. For this reason, the production of amorphous drugs wit...
Autores principales: | Karagianni, Anna, Kachrimanis, Kyriakos, Nikolakakis, Ioannis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161132/ https://www.ncbi.nlm.nih.gov/pubmed/30029516 http://dx.doi.org/10.3390/pharmaceutics10030098 |
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