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Neutralizing Anti-Hemagglutinin Monoclonal Antibodies Induced by Gene-Based Transfer Have Prophylactic and Therapeutic Effects on Influenza Virus Infection

Hemagglutinin (HA) of influenza virus is a major target for vaccines. HA initiates the internalization of the virus into the host cell by binding to host sialic acid receptors; therefore, inhibition of HA can significantly prevent influenza virus infection. However, the high diversity of HA permits...

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Detalles Bibliográficos
Autores principales: Yamazaki, Tatsuya, Chiba, Joe, Akashi-Takamura, Sachiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161145/
https://www.ncbi.nlm.nih.gov/pubmed/29949942
http://dx.doi.org/10.3390/vaccines6030035