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Protective Cancer Vaccine Using Genetically Modified Hematopoietic Stem Cells

Hematopoietic stem cells (HSCs) yield both the myeloid and lymphoid lineages of blood cells and can be reprogrammed into tumor antigen (Ag)-specific CD8(+) cytotoxic T lymphocytes (CTLs) to prevent tumor growth. However, the optimal approach for differentiating tumor Ag-specific CTLs from HSCs, such...

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Detalles Bibliográficos
Autores principales: Xiong, Xiaofang, Das, Jugal Kishor, Song, Jianyong, Ni, Bing, Ren, Xingcong, Yang, Jin-Ming, Song, Jianxun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161162/
https://www.ncbi.nlm.nih.gov/pubmed/29986440
http://dx.doi.org/10.3390/vaccines6030040