Effects of Formulation and Process Variables on Gastroretentive Floating Tablets with A High-Dose Soluble Drug and Experimental Design Approach

To develop sustained release gastro-retentive effervescent floating tablets (EFT), a quality-based experimental design approach was utilized during the composing of a hydrophilic matrix loaded with a high amount of a highly water-soluble model drug, metformin HCl. Effects of the amount of polyethyle...

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Detalles Bibliográficos
Autores principales: Thapa, Prakash, Jeong, Seong Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161171/
https://www.ncbi.nlm.nih.gov/pubmed/30227678
http://dx.doi.org/10.3390/pharmaceutics10030161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161171/
https://www.ncbi.nlm.nih.gov/pubmed/30227678
http://dx.doi.org/10.3390/pharmaceutics10030161

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