Tailoring Formulations for Intranasal Nose-to-Brain Delivery: A Review on Architecture, Physico-Chemical Characteristics and Mucociliary Clearance of the Nasal Olfactory Mucosa

The blood-brain barrier and the blood-cerebrospinal fluid barrier are major obstacles in central nervous system (CNS) drug delivery, since they block most molecules from entering the brain. Alternative drug delivery routes like intraparenchymal or intrathecal are invasive methods with a remaining ri...

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Detalles Bibliográficos
Autores principales: Gänger, Stella, Schindowski, Katharina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161189/
https://www.ncbi.nlm.nih.gov/pubmed/30081536
http://dx.doi.org/10.3390/pharmaceutics10030116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161189/
https://www.ncbi.nlm.nih.gov/pubmed/30081536
http://dx.doi.org/10.3390/pharmaceutics10030116

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