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Amorphous Nanoparticulate Formulation of Sirolimus and Its Tablets
Nanocrystallization and amorphization have proven to be two effective strategies to improve the bioavailability of water-insoluble drugs. The purpose of our work was to develop a nano-formulated tablet of sirolimus (SRL) for enhanced dissolution. Amorphous SRL nanocomposites were prepared using anti...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161202/ https://www.ncbi.nlm.nih.gov/pubmed/30208637 http://dx.doi.org/10.3390/pharmaceutics10030155 |