Development and Evaluation of Raloxifene-Hydrochloride-Loaded Supersaturatable SMEDDS Containing an Acidifier

Raloxifene hydrochloride (RLH) was formulated into a pH-modified supersaturatable self-microemulsifying drug delivery system (S-SMEDDS) to increase drug solubility and dissolution rate. Optimal formulations of pH-modified S-SMEDDSs were developed by incorporating hydroxypropyl-cellulose-L as a preci...

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Detalles Bibliográficos
Autores principales: Lee, Jong-Hwa, Kim, Hak Hyung, Cho, Young Ho, Koo, Tae-Sung, Lee, Gye Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161204/
https://www.ncbi.nlm.nih.gov/pubmed/29966249
http://dx.doi.org/10.3390/pharmaceutics10030078

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161204/
https://www.ncbi.nlm.nih.gov/pubmed/29966249
http://dx.doi.org/10.3390/pharmaceutics10030078

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