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Development and Evaluation of Raloxifene-Hydrochloride-Loaded Supersaturatable SMEDDS Containing an Acidifier
Raloxifene hydrochloride (RLH) was formulated into a pH-modified supersaturatable self-microemulsifying drug delivery system (S-SMEDDS) to increase drug solubility and dissolution rate. Optimal formulations of pH-modified S-SMEDDSs were developed by incorporating hydroxypropyl-cellulose-L as a preci...
Autores principales: | Lee, Jong-Hwa, Kim, Hak Hyung, Cho, Young Ho, Koo, Tae-Sung, Lee, Gye Won |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161204/ https://www.ncbi.nlm.nih.gov/pubmed/29966249 http://dx.doi.org/10.3390/pharmaceutics10030078 |
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