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Validation of Model-Based Melt Viscosity in Hot-Melt Extrusion Numerical Simulation

A validation for the use of model-based melt viscosity in hot-melt extrusion numerical simulations was presented. Here, the melt viscosity of an amorphous solid dispersion (ASD) was calculated by using its glass transition temperature (T(g)) and the rheological flow profile of the pure polymeric mat...

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Detalles Bibliográficos
Autores principales: Bochmann, Esther S., Gryczke, Andreas, Wagner, Karl G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161212/
https://www.ncbi.nlm.nih.gov/pubmed/30126193
http://dx.doi.org/10.3390/pharmaceutics10030132