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Characterization of CYPs and UGTs Involved in Human Liver Microsomal Metabolism of Osthenol

Osthenol is a prenylated coumarin isolated from the root of Angelica koreana and Angelica dahurica, and is an O-demethylated metabolite of osthole in vivo. Its various pharmacological effects have been reported previously. The metabolic pathway of osthenol was partially confirmed in rat osthole stud...

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Detalles Bibliográficos
Autores principales: Cho, Pil Joung, Paudel, Sanjita, Lee, Doohyun, Jin, Yun Ji, Jo, GeunHyung, Jeong, Tae Cheon, Lee, Sangkyu, Lee, Taeho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161247/
https://www.ncbi.nlm.nih.gov/pubmed/30200214
http://dx.doi.org/10.3390/pharmaceutics10030141