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Characterization of CYPs and UGTs Involved in Human Liver Microsomal Metabolism of Osthenol
Osthenol is a prenylated coumarin isolated from the root of Angelica koreana and Angelica dahurica, and is an O-demethylated metabolite of osthole in vivo. Its various pharmacological effects have been reported previously. The metabolic pathway of osthenol was partially confirmed in rat osthole stud...
Autores principales: | Cho, Pil Joung, Paudel, Sanjita, Lee, Doohyun, Jin, Yun Ji, Jo, GeunHyung, Jeong, Tae Cheon, Lee, Sangkyu, Lee, Taeho |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161247/ https://www.ncbi.nlm.nih.gov/pubmed/30200214 http://dx.doi.org/10.3390/pharmaceutics10030141 |
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