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Engineering Cocrystals of Poorly Water-Soluble Drugs to Enhance Dissolution in Aqueous Medium

Biopharmaceutics Classification System (BCS) Class II and IV drugs suffer from poor aqueous solubility and hence low bioavailability. Most of these drugs are hydrophobic and cannot be developed into a pharmaceutical formulation due to their poor aqueous solubility. One of the ways to enhance the aqu...

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Detalles Bibliográficos
Autores principales: Sathisaran, Indumathi, Dalvi, Sameer Vishvanath
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161265/
https://www.ncbi.nlm.nih.gov/pubmed/30065221
http://dx.doi.org/10.3390/pharmaceutics10030108