Pharmacokinetic Drug-Drug Interaction and Responsible Mechanism between Memantine and Cimetidine

A sensitive and simple chromatography-tandem mass spectrometry (LC-MS/MS) method was developed to evaluate memantine in rat plasma. Memantine and propranolol (internal standard) in rat plasma was extracted using a methanol precipitation method. The standard curve value was 0.2–1000 ng/mL and selecti...

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Detalles Bibliográficos
Autores principales: Choi, Young A., Song, Im-Sook, Choi, Min-Koo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161283/
https://www.ncbi.nlm.nih.gov/pubmed/30082658
http://dx.doi.org/10.3390/pharmaceutics10030119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161283/
https://www.ncbi.nlm.nih.gov/pubmed/30082658
http://dx.doi.org/10.3390/pharmaceutics10030119

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