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Pharmacokinetic Drug-Drug Interaction and Responsible Mechanism between Memantine and Cimetidine

A sensitive and simple chromatography-tandem mass spectrometry (LC-MS/MS) method was developed to evaluate memantine in rat plasma. Memantine and propranolol (internal standard) in rat plasma was extracted using a methanol precipitation method. The standard curve value was 0.2–1000 ng/mL and selecti...

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Detalles Bibliográficos
Autores principales:	Choi, Young A., Song, Im-Sook, Choi, Min-Koo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161283/ https://www.ncbi.nlm.nih.gov/pubmed/30082658 http://dx.doi.org/10.3390/pharmaceutics10030119

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