Activation-induced Markers Detect Vaccine-Specific CD4(+) T Cell Responses Not Measured by Assays Conventionally Used in Clinical Trials

Immunogenicity of T cell-inducing vaccines, such as viral vectors or DNA vaccines and Bacillus Calmette-Guérin (BCG), are frequently assessed by cytokine-based approaches. While these are sensitive methods that have shown correlates of protection in various vaccine studies, they only identify a smal...

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Detalles Bibliográficos
Autores principales: Bowyer, Georgina, Rampling, Tommy, Powlson, Jonathan, Morter, Richard, Wright, Daniel, Hill, Adrian V.S., Ewer, Katie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161310/
https://www.ncbi.nlm.nih.gov/pubmed/30065162
http://dx.doi.org/10.3390/vaccines6030050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161310/
https://www.ncbi.nlm.nih.gov/pubmed/30065162
http://dx.doi.org/10.3390/vaccines6030050

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