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Recent advances in searching c-Myc transcriptional cofactors during tumorigenesis

BACKGROUND: The mechanism by which c-Myc exerts its oncogenic functions is not completely clear and different hypotheses are still under investigation. The knowledge of the capacity of c-Myc to bind exclusively E-box sequences determined the discrepancy between, on the one hand, genomic studies show...

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Detalles Bibliográficos
Autores principales: Caforio, Matteo, Sorino, Cristina, Iacovelli, Stefano, Fanciulli, Maurizio, Locatelli, Franco, Folgiero, Valentina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161371/
https://www.ncbi.nlm.nih.gov/pubmed/30261904
http://dx.doi.org/10.1186/s13046-018-0912-2