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A comprehensive analysis of 195 DNA methylomes reveals shared and cell-specific features of partially methylated domains

BACKGROUND: Partially methylated domains are extended regions in the genome exhibiting a reduced average DNA methylation level. They cover gene-poor and transcriptionally inactive regions and tend to be heterochromatic. We present a comprehensive comparative analysis of partially methylated domains...

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Detalles Bibliográficos
Autores principales: Salhab, Abdulrahman, Nordström, Karl, Gasparoni, Gilles, Kattler, Kathrin, Ebert, Peter, Ramirez, Fidel, Arrigoni, Laura, Müller, Fabian, Polansky, Julia K., Cadenas, Cristina, G.Hengstler, Jan, Lengauer, Thomas, Manke, Thomas, Walter, Jörn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161375/
https://www.ncbi.nlm.nih.gov/pubmed/30266094
http://dx.doi.org/10.1186/s13059-018-1510-5