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Cerebrospinal fluid phosphorylated tau, visinin-like protein-1, and chitinase-3-like protein 1 in mild cognitive impairment and Alzheimer’s disease

BACKGROUND: Visinin-like protein-1 (VILIP-1) and chitinase-3-like protein 1 (CHI3L1 or YKL-40) in cerebrospinal fluid (CSF) are newly discovered markers indicating neuronal damage and microglial activation, respectively. Phosphorylated tau (p-tau) reflects the neuropathology of Alzheimer’s disease (...

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Detalles Bibliográficos
Autores principales: Zhang, Hua, Ng, Kok Pin, Therriault, Joseph, Kang, Min Su, Pascoal, Tharick A., Rosa-Neto, Pedro, Gauthier, Serge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161434/
https://www.ncbi.nlm.nih.gov/pubmed/30311914
http://dx.doi.org/10.1186/s40035-018-0127-7