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Nasal delivery of nerve growth factor rescue hypogonadism by up-regulating GnRH and testosterone in aging male mice

BACKGROUND: Nerve growth factor (NGF) plays essential roles in regulating the development and maintenance of central sympathetic and sensory neurons. However, the effects of NGF on hypogonadism remain unexplored. METHODS: To assess the effects of NGF on hypogonadism, we established a convenient and...

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Detalles Bibliográficos
Autores principales: Luo, Jiao, Yang, Yan, Zhang, Tiantian, Su, Zhijian, Yu, Dan, Lin, Qilian, Chen, Haolin, Zhang, Qihao, Xiang, Qi, Xue, Wei, Ge, Renshan, Huang, Yadong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161474/
https://www.ncbi.nlm.nih.gov/pubmed/30131307
http://dx.doi.org/10.1016/j.ebiom.2018.08.021