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Validation of MRC Centre MRI calf muscle fat fraction protocol as an outcome measure in CMT1A

OBJECTIVE: To translate the quantitative MRC Centre MRI protocol in Charcot-Marie-Tooth disease type 1A (CMT1A) to a second site; validate its responsiveness in an independent cohort; and test the benefit of participant stratification to increase outcome measure responsiveness. METHODS: Three health...

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Detalles Bibliográficos
Autores principales: Morrow, Jasper M., Evans, Matthew R.B., Grider, Tiffany, Sinclair, Christopher D.J., Thedens, Daniel, Shah, Sachit, Yousry, Tarek A., Hanna, Michael G., Nopoulos, Peggy, Thornton, John S., Shy, Michael E., Reilly, Mary M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161551/
https://www.ncbi.nlm.nih.gov/pubmed/30120135
http://dx.doi.org/10.1212/WNL.0000000000006214