The Antidiabetic Drug Lobeglitazone Protects Mice From Lipogenesis-Induced Liver Injury via Mechanistic Target of Rapamycin Complex 1 Inhibition

Non-alcoholic fatty liver disease (NAFLD) is a metabolic disorder closely linked with type II diabetes (T2D). The progression of NAFLD is associated with the induction of lipogenesis through hyperactivation of the mechanistic target of rapamycin complex 1 (mTORC1) pathway. An increase in lipogenesis...

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Detalles Bibliográficos
Autores principales: Lee, Yu Seol, Park, Jeong Su, Lee, Da Hyun, Lee, Dong-Kyu, Kwon, Sung Won, Lee, Byung-Wan, Bae, Soo Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161559/
https://www.ncbi.nlm.nih.gov/pubmed/30298052
http://dx.doi.org/10.3389/fendo.2018.00539

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161559/
https://www.ncbi.nlm.nih.gov/pubmed/30298052
http://dx.doi.org/10.3389/fendo.2018.00539

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