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Fine mapping MHC associations in Graves’ disease and its clinical subtypes in Han Chinese

BACKGROUND: The classical human leucocyte antigen (HLA) genes were the most important genetic determinant for Graves’ disease (GD). The aim of the study was to fine map causal variants of the HLA genes. METHODS: We applied imputation with a Pan-Asian HLA reference panel to thoroughly investigate the...

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Detalles Bibliográficos
Autores principales: Chu, Xun, Yang, Minjun, Song, Zhen-Ju, Dong, Yan, Li, Chong, Shen, Min, Zhu, Yong-Qiang, Song, Huai-Dong, Chen, Sai-Juan, Chen, Zhu, Huang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161647/
https://www.ncbi.nlm.nih.gov/pubmed/29987165
http://dx.doi.org/10.1136/jmedgenet-2017-105146