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Non-classical monocytes as mediators of tissue destruction in arthritis

OBJECTIVES: Bone destruction in rheumatoid arthritis is mediated by osteoclasts (OC), which are derived from precursor cells of the myeloid lineage. The role of the two monocyte subsets, classical monocytes (expressing CD115, Ly6C and CCR2) and non-classical monocytes (which are CD115 positive, but...

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Detalles Bibliográficos
Autores principales: Puchner, Antonia, Saferding, Victoria, Bonelli, Michael, Mikami, Yohei, Hofmann, Melanie, Brunner, Julia S, Caldera, Michael, Goncalves-Alves, Eliana, Binder, Nikolaus B, Fischer, Anita, Simader, Elisabeth, Steiner, Carl-Walter, Leiss, Harald, Hayer, Silvia, Niederreiter, Birgit, Karonitsch, Thomas, Koenders, Marije I, Podesser, Bruno K, O’Shea, John J, Menche, Jörg, Smolen, Josef S, Redlich, Kurt, Blüml, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161666/
https://www.ncbi.nlm.nih.gov/pubmed/29959183
http://dx.doi.org/10.1136/annrheumdis-2018-213250