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Using bioinformatics tools for the discovery of Dengue RNA-dependent RNA polymerase inhibitors

BACKGROUND: Dengue fever has rapidly manifested into a serious global health concern. The emergence of various viral serotypes has prompted the urgent need for innovative drug design techniques. Of the viral non-structural enzymes, the NS5 RNA-dependent RNA polymerase has been established as a promi...

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Detalles Bibliográficos
Autores principales: Nncube, Nomagugu B., Ramharack, Pritika, Soliman, Mahmoud E.S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161702/
https://www.ncbi.nlm.nih.gov/pubmed/30280009
http://dx.doi.org/10.7717/peerj.5068