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Doxorubicin-loaded dextran-based nano-carriers for highly efficient inhibition of lymphoma cell growth and synchronous reduction of cardiac toxicity

PURPOSE: Cardiac side effects of doxorubicin (Dox) have limited its clinical application. The aim of this study was to explore new Dox-loaded dextran-based nano-carriers (NCs) in efficiently targeting tumor growth with less cardiac toxicity. METHODS: Inspired by recent reports that polymeric NCs cou...

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Detalles Bibliográficos
Autores principales: Fang, Ying, Wang, Hao, Dou, Hong-Jing, Fan, Xing, Fei, Xiao-Chun, Wang, Lei, Cheng, Shu, Janin, Anne, Wang, Li, Zhao, Wei-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161723/
https://www.ncbi.nlm.nih.gov/pubmed/30288040
http://dx.doi.org/10.2147/IJN.S161203