Design and development of Nrf2 modulators for cancer chemoprevention and therapy: a review

A major cell defense mechanism against oxidative and xenobiotic stress is mediated by the Nrf2/Keap1 signaling pathway. The Nrf2/Keap1 pathway regulates gene expression of many cytoprotective and detoxifying enzymes, thus playing a pivotal role in maintaining redox cellular homeostasis. Many disease...

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Detalles Bibliográficos
Autores principales: Sova, Matej, Saso, Luciano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161735/
https://www.ncbi.nlm.nih.gov/pubmed/30288023
http://dx.doi.org/10.2147/DDDT.S172612

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161735/
https://www.ncbi.nlm.nih.gov/pubmed/30288023
http://dx.doi.org/10.2147/DDDT.S172612

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