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Murrangatin suppresses angiogenesis induced by tumor cell–derived media and inhibits AKT activation in zebrafish and endothelial cells

INTRODUCTION: Lung cancer is a major cancer type and a leading cause of cancer-related death. Angiogenesis plays a crucial role in lung cancer pathogenesis and its inhibition is beneficial to patients. MATERIALS AND METHODS: Murrangatin, a natural product, can inhibit the proliferation of lung cance...

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Detalles Bibliográficos
Autores principales: Long, Weiqing, Wang, Mingjun, Luo, Xiongming, Huang, Guixian, Chen, Jianwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161741/
https://www.ncbi.nlm.nih.gov/pubmed/30288018
http://dx.doi.org/10.2147/DDDT.S145956