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Pairs of Adjacent Conserved Noncoding Elements Separated by Conserved Genomic Distances Act as Cis-Regulatory Units

Comparative genomic studies have identified thousands of conserved noncoding elements (CNEs) in the mammalian genome, many of which have been reported to exert cis-regulatory activity. We analyzed ∼5,500 pairs of adjacent CNEs in the human genome and found that despite divergence at the nucleotide s...

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Detalles Bibliográficos
Autores principales: Li, Lifei, Barth, Nicolai K H, Hirth, Eva, Taher, Leila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161761/
https://www.ncbi.nlm.nih.gov/pubmed/30184074
http://dx.doi.org/10.1093/gbe/evy196