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Intratumor heterogeneity of HMCN1 mutant alleles associated with poor prognosis in patients with breast cancer
Human breast cancers comprise a complex and highly heterogeneous population of tumor cells. Intratumor heterogeneity is an underlying cause of resistance to effective therapies and disease recurrence. To explore prognostic factors based on intratumor heterogeneity, we analyzed genomic mutations in b...
Autores principales: | Kikutake, Chie, Yoshihara, Minako, Sato, Tetsuya, Saito, Daisuke, Suyama, Mikita |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161790/ https://www.ncbi.nlm.nih.gov/pubmed/30279964 http://dx.doi.org/10.18632/oncotarget.26071 |
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