A safety study of newly generated anti-podoplanin-neutralizing antibody in cynomolgus monkey (Macaca fascicularis)

Hematogenous metastases are enhanced by platelet aggregation induced by tumor cell-platelet interaction. Podoplanin is a key molecule to enhance the platelet aggregation and interacts with C-type lectin-like receptor 2 (CLEC-2) on platelet via PLAG domains. Our previous reports have shown that block...

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Detalles Bibliográficos
Autores principales: Ukaji, Takao, Takemoto, Ai, Katayama, Ryohei, Takeuchi, Kengo, Fujita, Naoya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161800/
https://www.ncbi.nlm.nih.gov/pubmed/30279963
http://dx.doi.org/10.18632/oncotarget.26055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161800/
https://www.ncbi.nlm.nih.gov/pubmed/30279963
http://dx.doi.org/10.18632/oncotarget.26055

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