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Impact of structural prior knowledge in SNV prediction: Towards causal variant finding in rare disease
Can structural information of proteins generate essential features for predicting the deleterious effect of a single nucleotide variant (SNV) independent of the known existence of the SNV in diseases? In this work, we answer the question by examining the performance of features generated from prior...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161878/ https://www.ncbi.nlm.nih.gov/pubmed/30265692 http://dx.doi.org/10.1371/journal.pone.0204101 |