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Selective human inhibitors of ATR and ATM render Leishmania major promastigotes sensitive to oxidative damage

All cellular processes, including those involved in normal cell metabolism to those responsible for cell proliferation or death, are finely controlled by cell signaling pathways, whose core proteins constitute the family of phosphatidylinositol 3-kinase-related kinases (PIKKs). Ataxia Telangiectasia...

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Detalles Bibliográficos
Autores principales: da Silva, Raíssa Bernardes, Machado, Carlos Renato, Rodrigues, Aldo Rogelis Aquiles, Pedrosa, André Luiz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161909/
https://www.ncbi.nlm.nih.gov/pubmed/30265735
http://dx.doi.org/10.1371/journal.pone.0205033