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Kappa opioid regulation of depressive-like behavior during acute withdrawal and protracted abstinence from ethanol

The dynorphin/kappa opioid receptor (DYN/KOR) system appears to be a key mediator of the behavioral effects of chronic exposure to alcohol. Although KOR opioid receptor antagonists have been shown to decrease stress-related behaviors in animal models during acute ethanol withdrawal, the role of the...

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Detalles Bibliográficos
Autores principales: Jarman, Sorscha K., Haney, Alison M., Valdez, Glenn R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161915/
https://www.ncbi.nlm.nih.gov/pubmed/30265734
http://dx.doi.org/10.1371/journal.pone.0205016