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Kappa opioid regulation of depressive-like behavior during acute withdrawal and protracted abstinence from ethanol
The dynorphin/kappa opioid receptor (DYN/KOR) system appears to be a key mediator of the behavioral effects of chronic exposure to alcohol. Although KOR opioid receptor antagonists have been shown to decrease stress-related behaviors in animal models during acute ethanol withdrawal, the role of the...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161915/ https://www.ncbi.nlm.nih.gov/pubmed/30265734 http://dx.doi.org/10.1371/journal.pone.0205016 |