Human T cell receptor occurrence patterns encode immune history, genetic background, and receptor specificity

The T cell receptor (TCR) repertoire encodes immune exposure history through the dynamic formation of immunological memory. Statistical analysis of repertoire sequencing data has the potential to decode disease associations from large cohorts with measured phenotypes. However, the repertoire perturb...

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Detalles Bibliográficos
Autores principales: DeWitt, William S, Smith, Anajane, Schoch, Gary, Hansen, John A, Matsen, Frederick A, Bradley, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Computational and Systems Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162092/
https://www.ncbi.nlm.nih.gov/pubmed/30152754
http://dx.doi.org/10.7554/eLife.38358

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162092/
https://www.ncbi.nlm.nih.gov/pubmed/30152754
http://dx.doi.org/10.7554/eLife.38358

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