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Intestinal damage precedes mucosal immune dysfunction in SIV infection

HIV and pathogenic SIV infection are characterized by mucosal dysfunction including epithelial barrier damage, loss of Th17 cells, neutrophil infiltration, and microbial translocation with accompanying inflammation. However, it is unclear how and when these contributing factors occur relative to one...

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Detalles Bibliográficos
Autores principales: Hensley-McBain, Tiffany, Berard, Alicia R., Manuzak, Jennifer A., Miller, Charlene J., Zevin, Alexander S., Polacino, Patricia, Gile, Jillian, Agricola, Brian, Cameron, Mark, Hu, Shiu-Lok, Estes, Jacob D., Reeves, R. Keith, Smedley, Jeremy, Keele, Brandon F., Burgener, Adam D., Klatt, Nichole R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162106/
https://www.ncbi.nlm.nih.gov/pubmed/29907866
http://dx.doi.org/10.1038/s41385-018-0032-5